Claritin® Tolerability
and Dosing


  • Just 1 dose can provide 24-hour allergy symptom relief1
  • Both doctors and patients agree that ease of use and once-daily dosing can enhance treatment adherence2
Significant improvements in daytime and night-time symptoms compared with cetirizine chart

Loratadine, the active ingredient in Claritin®, provides non-drowsy allergy symptom relief3

  • Significantly less sedation during the workday compared with cetirizine

*P<0.01; P =0.02; P =0.04; §P =0.01.

Adapted from Salmun et al, 2000.

A randomized, double-blind, parallel-group study involving 60 patients (≥12 years) with active allergic rhinitis.

qd=once daily.

Loratadine, the active ingredient in Claritin®, has no significant effect on driving ability4

Loratadine, the active ingredient in Claritin®, has no significant effect on driving ability4

  • In a clinical study, Claritin® had no significant effect on weaving motion or deviation of speed4
  • Claritin® has no significant effects on psychometric performance4
  • Additional studies have confirmed that Claritin® has no significant effect on driving ability or psychometric performance5-7

Claritin® is acceptable for pilot use by the FAA.8

Adapted from Ramaekers et al, 1992.

A 6-way, double-blind, cross-over trial involving 16 healthy subjects (22 to 35 years).

SEM=standard error of the mean.

Chart comparison

Claritin® has different label warnings than competitors1,9-11

*Based on selected attributes of US OTC Drug Facts labels—when used as directed.

Claritin® is considered safe and well tolerated* with an adverse event profile similar to placebo12

Rates of adverse events reported for Claritin® in placebo-controlled AR clinical trials were similar to placebo.

*When used as directed.

AEs occurring with a frequency of >2% in placebo-controlled AR clinical trials in patients aged 12 years and older.

AEs=adverse events; AR=allergic rhinitis.


Claritin® offers allergy relief for kids and adults in a variety of forms and flavors.

Help your patients tackle their tough allergy symptoms with samples and coupons for Claritin® products.

Samples and coupons - Collection of Claritin packages

References: 1. Claritin® Drug Facts. NDA019658. 2. Ciprandi G. Clinical utility and patient adherence with ebastine for allergic rhinitis. Patient Prefer Adherence. 2010;4:389-395. 3. Salmun LM, Gates D, Scharf M, et al. Loratadine versus cetirizine: assessment of somnolence and motivation during the workday. Clin Ther. 2000;22(5):573-582. 4. Ramaekers JG, Uiterwijk MMC, O’Hanlon JF. Effects of loratadine and cetirizine on actual driving and psychometric test performance, and EEG during driving. Eur J Clin Pharmacol. 1992;42(4):363-369. 5. Verster JC, Volkerts ER. Antihistamines and driving ability: evidence from on-the-road driving studies during normal traffic. Ann Allergy Asthma Immunol. 2004;92(3):294-303. doi:10.1016/S1081-1206(10)61566-9 6. Popescu F-D. H1 antihistamines and driving. J Med Life. 2008;1(3):262-268. 7. Kay GG, Harris AG. Loratadine: a non-sedating antihistamine. Review of its effects on cognition, psychomotor performance, mood and sedation. Clin Exp Allergy. 1999;29 Suppl 3:147-150. doi:10.1046/j.1365-2222.1999.0290s3147.x 8. Federal Aviation Administration. What over-the-counter (OTC) medications can I take and still be safe to fly? Accessed August 4, 2021. https://www.faa.gov/licenses_certificates/medical_certification/media/OTCMedicationsforPilots.pdf 9. Zyrtec® Drug Facts. NDC 50580-726-36. 10. Allegra® Allergy Drug Facts. 11. Xyzal® Drug Facts. Accessed December 14, 2021. https://www.xyzal.com/hcp/download/DrugFactsLabel.pdf 12. Claritin®. Prescribing Information. Schering Corporation; 2000.