Claritin®
Tolerability

 

 

Claritin®
Tolerability

 

A Clear Choice for Tolerability and Convenience

  • Just 1 dose can provide 24 hour allergy symptom relief1
  • Both doctors and patients agree that ease of use and once-daily dosing can enhance treatment adherence2

A Clear Choice for Tolerability and Convenience

  • Just 1 dose can provide 24 hour allergy symptom relief1
  • Both doctors and patients agree that ease of use and once-daily dosing can enhance treatment adherence2

Loratadine, the Active Ingredient in Claritin®
Provides Non-Drowsy Allergy Symptom Relief3

Loratadine, the Active Ingredient in Claritin®, Provides Non-Drowsy Allergy Symptom Relief3

Chart comparing sedation effect of loratadine with cetirizine.
Chart comparing sedation effect of loratadine with cetirizine.

 

  • Significantly less sedation during the workday compared with cetirizine.

*P<0.01; †P =0.02; ‡P =0.04; §P =0.01.

Adapted from Salmun et al, 2000.

A randomized, double-blind, parallel-group study involving 60 patients (≥12 years) with active allergic rhinitis.

qd=once daily.

  • Significantly less sedation during the workday compared with cetirizine.

 

*P<0.01; †P =0.02; ‡P =0.04; §P =0.01.

Adapted from Salmun et al, 2000.

A randomized, double-blind, parallel-group study involving 60 patients (≥12 years) with active allergic rhinitis.

qd=once daily.

 

Loratadine, the Active Ingredient in Claritin®,
has no Significant Effect on Driving Ability4

Loratadine, the Active Ingredient in Claritin®, has no Significant Effect on Driving Ability4

Weaving motion and deviation of speed chart. 
Weaving motion and deviation of speed chart. 

 

  • In a clinical study, Claritin® had no significant effect on weaving motion or deviation of speed.4
  • Claritin® has no significant effects on psychometric performance.4
  • Additional studies have confirmed that Claritin® has no significant effect on driving ability or psychometric performance.5-7

 

Claritin® is acceptable for pilot use by the FAA.8

Adapted from Ramaekers et al, 1992.

A 6-way, double-blind, cross-over trial involving 16 healthy subjects (22 to 35 years).

SEM=standard error of the mean.

 

Claritin® has Different Label
Warnings than Competitors1, 9-11

Claritin® has Different Label Warnings than Competitors1, 9-11

Table comparing label warnings of Claritin® and other brands.
Table comparing label warnings of Claritin® and other brands.

 

*Based on selected attributes of US OTC Drug Facts labels—when used as directed.

 

Claritin® is considered safe and well tolerated* with an adverse event profile similar to placebo.12

Rates of adverse events reported for Claritin® in placebo-controlled AR clinical trials were similar to placebo.

Rates of adverse events reported for Claritin® in placebo-controlled AR clinical trials were similar to placebo.

*When used as directed.

AEs occurring with a frequency of >2% in placebo-controlled AR clinical trials in patients aged 12 years and older.

AEs=adverse events; AR=allergic rhinitis.

 

 

 

 

 

 

Order Samples and Coupons for Your Patients

Claritin® offers allergy relief for kids and adults in a variety of forms and flavors. Help your patients tackle their tough allergy symptoms with samples and coupons for Claritin® products. Your patients have options with different Claritin® products!

Order Patient Resources

 

 

Order Samples and Coupons for Your Patients

Claritin® offers allergy relief for kids and adults in a variety of forms and flavors. Help your patients tackle their tough allergy symptoms with samples and coupons for Claritin® products.

Order Patient Resources

 

 

References

  1. Claritin® Drug Facts. NDA019658.
  2. Ciprandi G. Clinical utility and patient adherence with ebastine for allergic rhinitis. Patient Prefer Adherence. 2010;4:389-395.
  3. Salmun LM, Gates D, Scharf M, et al. Loratadine versus cetirizine: assessment of somnolence and motivation during the workday. Clin Ther. 2000;22(5):573-582.
  4. Ramaekers JG, Uiterwijk MMC, O’Hanlon JF. Effects of loratadine and cetirizine on actual driving and psychometric test performance, and EEG during driving. Eur J Clin Pharmacol. 1992;42(4):363-369.
  5. Verster JC, Volkerts ER. Antihistamines and driving ability: evidence from on‑the‑road driving studies during normal traffic. Ann Allergy Asthma Immunol. 2004;92(3):294‑304. doi:10.1016/S1081‑1206(10)61566‑9.
  6. Popescu, Florin‑Dan. “H1 antihistamines and driving.” Journal of Medicine and Life, 2008, Vol. 1(3), pp. 262–268.
  7. Kay GG, Harris AG. Loratadine: a non-sedating antihistamine. Review of its effects on cognition, psychomotor performance, mood and sedation. Clin Exp Allergy. 1999;29 Suppl 3:147-150. doi:10.1046/j.1365-2222.1999.0290s3147.x
  8. Federal Aviation Administration. What over-the-counter (OTC) medications can I take and still be safe to fly? Accessed August 4, 2021. 
  9. Zyrtec® Drug Facts. NDC 50580-726-36.
  10. Allegra® Allergy Drug Facts.
  11. Xyzal® Drug Facts. Accessed December 14, 2021. 
  12. Claritin®. Prescribing Information. Schering Corporation; 2000.